IVF-ICSI

IVF Michigan Fertility Center's state-of-the-art facility utilizes the latest technologies including an in-house embryo genetic testing laboratory allowing for embryo micromanipulation in addition to a lab for sperm processing. IVF Michigan Fertility Center is committed to fulfilling dreams of parenthood by delivering compassionate and personalized fertility treatments that are provided by a team of specialized medical experts equipped with the most advanced technology and innovative medical protocols.

With over 60 years of collective experience and locations in Bloomfield Hills, Ann Arbor, Dearborn, Saginaw and Toledo, OH, the physicians of IVF Michigan Fertility Center are available to help couples throughout the Midwest and abroad. Other treatment options available at IVF Michigan Fertility Center include Mini IVF, Natural Cycle IVF, IUI, Gender Selection, comprehensive chromosomal screening through Pre-Implantation Genetic Screening (PGS), Screening for hereditary diseases through PGD, Male Infertility and much more.

In Vitro Fertilization (IVF) is the process of collecting eggs from a woman and sperm from a man and fertilizing them in the Embryology Laboratory. In order to increase chances of fertilization, a single sperm is injected into each of the retrieved eggs using a precision needle in a process called Intra-Cytoplasmic Sperm Injection (ICSI).

IVF-ICSI IVF in Michigan IVF Michigan Fertility Center Fakih Shamma Hammoud


What are the benefits of IVF-ICSI?

ICSI has been shown to improve the fertilization rate in a number of cases. It may be especially helpful in the following cases: 

  • Previous failed fertilization
  • Low sperm count
  • Poor sperm motility
  • High amount of abnormal sperm
  • Retrograde ejaculation
  • Vasectomy
  • Immunological factors
  • Other conditions that prevent fertilization of the egg

What are the steps and duration of an IVF-ICSI cycle?

During the initial consultation, an Infertility Specialist will take a full medical history and may perform a check-up that includes an ultrasound scan and blood tests to check hormonal levels. Based on the medical history and clinical exams, a personalized treatment plan is constructed. If the IVF Specialist suspects that infertility may be attributed to a Male Factor, a  semen analysis will be conducted before treatment and the protocol will be altered as necessary. 

In the case that IVF-ICSI is the right treatment for you, the following will take place over 21-25 days. 

IVF ICSI IVF Michigan Fertility Center Hammoud Shamma Fakih

Ovarian Stimulation (7 to 10 days):

On Day 2 or 3 of the Menstrual cycle, medication is prescribed to stimulate the growth of multiple follicles in the ovaries. During this time, follicular growth is monitored through ultrasound as they develop into eggs and hormone levels are tracked through blood tests. Medication protocols are changed as needed. 36 – 40 hours before the scheduled Egg Retrieval, a “trigger” shot is given to induce maturation of the eggs within a scheduled timeframe.

IVF ICSI IVF Michigan Fertility Center Hammoud Shamma Fakih

Egg Retrieval (OPU):

Eggs are retrieved using a thin ultrasound-guided needle during a short procedure under sedation. The number of eggs retrieved depends on the body's response to the medication.

IVF ICSI IVF Michigan Fertility Center Hammoud Shamma Fakih

Sperm Collection and ICSI:

On the day of Egg Retrieval, a semen sample is taken to fertilize the retrieved eggs. To increase chances of fertilization, a single sperm is injected into each egg using a precision needle in a method called ICSI.

IVF ICSI IVF Michigan Fertility Center Hammoud Shamma Fakih

Possible Genetic Testing (GT):

If Pre-Implantation Genetic Screening (PGS) will be completed chromosomal screening (with the possibility of Gender Selection) or Pre-Implantation Genetic Diagnosis (PGD) will be completed to prevent passing on a hereditary disease, 3 to 5 days after the Egg Retrieval, a biopsy is taken from each embryo and tested in our Genetics Lab. The healthy embryos are then transferred to the uterus.

IVF ICSI IVF Michigan Fertility Center Hammoud Shamma Fakih

Embryo Transfer (ET):

Embryo Transfer is a minor procedure that does not require sedation. Following the procedure, hormone levels are tracked through blood test to confirm pregnancy. Any embryos that are not transferred may be frozen and used in a future cycle.

IVF-ICSI Diagram at IVF Michigan Fertility Center, steps of IVF

*The above dates are an approximation of an average cycle. 


Will every fertilized egg develop into a healthy embryo?

It is important to understand that not every egg collected will fertilize and develop into a viable embryo. It is common to have a variation of embryo stages and grades in embryos at any point after fertilization. After the eggs have fertilized, the embryologists will provide you with an assessment on the quality of the embryos.


Should I be considering IVF-ICSI? Do I have other options?

Each couple is unique and it is important to discuss your full medical history with an Infertility Specialist before making a decision. IVF Michigan Fertility Center is aware that experiencing difficulty in conceiving can be stressful, emotionally and financially, and we will do our part to help you and your spouse fulfill your dreams of parenthood.  Book an appointment at IVF Michigan Fertility Center Bloomfield Hills, Ann Arbor, Dearborn, Saginaw or Toledo, OH to discuss the best treatment options available for you.